The human SUV3 protein - what does it do?
Ewa Bartnik
Zakład Genetyki Uniwersytetu Warszawskiego
The human SUV3 gene encodes a DNA/RNA helicase whose function is
unknown, though its yeast homolog is involved in mitochondrial RNA
degradation. The human protein has been shown to map to chromosome
10q22.1, to be expressed in many tissues and to be primarily localized
in mitochondria. Experimental data have shown that the protein also
localizes to the nucleus and interacts with over a dozen proteins
involved in DNA maintenance and replication. We believe that it may be a
key cell cycle regulator, as siRNA for suv3 can cause apoptosis, whereas
the homogenization of two copies of the chromosomal area surrounding the
SUV3 gene in several types of tumour might suggest that it is a tumour
suppressor.
Recent progress in modelling the activities of HIV virus
Jan Komorowski
The Linnaeus Centre for Bioinformatics
Uppsala University, and
ICM, Warsaw University
Using a high-through approach we show preliminary results on
computational modelling the fundamental activities of the the HIV virus.
Seminarium odbędzie się w dniu 13 marca 2006 o godz. 12:30
w sali 3099 w siedzibie ICM na Wydziale Geologii,
ul. Żwirki i Wigury 91.
9 marca 2006